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Mitochondrial STAT3 regulates antioxidant gene expression through complex I‐derived NAD in triple negative breast cancer
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor with roles in inflammation and tumorigenicity. A fraction of STAT3 localizes in mitochondria, where it augments tumorigenesis via regulation of mitochondrial functions, including modulation of respiration and redox...
Autores principales: | Lahiri, Tanaya, Brambilla, Lara, Andrade, Joshua, Askenazi, Manor, Ueberheide, Beatrix, Levy, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096790/ https://www.ncbi.nlm.nih.gov/pubmed/33605027 http://dx.doi.org/10.1002/1878-0261.12928 |
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