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EWI‐2 controls nucleocytoplasmic shuttling of EGFR signaling molecules and miRNA sorting in exosomes to inhibit prostate cancer cell metastasis

Early and accurate diagnosis of prostate cancer (PCa) is extremely important, as metastatic PCa remains hard to treat. EWI‐2, a member of the Ig protein subfamily, is known to inhibit PCa cell migration. In this study, we found that EWI‐2 localized on both the cell membrane and exosomes regulates th...

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Detalles Bibliográficos
Autores principales: Fu, Chenying, Zhang, Qing, Wang, Ani, Yang, Songpeng, Jiang, Yangfu, Bai, Lin, Wei, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096798/
https://www.ncbi.nlm.nih.gov/pubmed/33605506
http://dx.doi.org/10.1002/1878-0261.12930