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A genomic mutation signature predicts the clinical outcomes of immunotherapy and characterizes immunophenotypes in gastrointestinal cancer

The association between genetic variations and immunotherapy benefit has been widely recognized, while such evidence in gastrointestinal cancer remains limited. We analyzed the genomic profile of 227 immunotherapeutic gastrointestinal cancer patients treated with immunotherapy, from the Memorial Slo...

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Detalles Bibliográficos
Autores principales: Jiao, Xi, Wei, Xin, Li, Shuang, Liu, Chang, Chen, Huan, Gong, Jifang, Li, Jian, Zhang, Xiaotian, Wang, Xicheng, Peng, Zhi, Qi, Changsong, Wang, Zhenghang, Wang, Yujiao, Wang, Yanni, Zhuo, Na, Zhang, Henghui, Lu, Zhihao, Shen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096820/
https://www.ncbi.nlm.nih.gov/pubmed/33947957
http://dx.doi.org/10.1038/s41698-021-00172-5