Atypical electrophysiological and behavioral responses to diazepam in a leading mouse model of Down syndrome

Mounting evidence implicates dysfunctional GABA(A)R-mediated neurotransmission as one of the underlying causes of learning and memory deficits observed in the Ts65Dn mouse model of Down syndrome (DS). The specific origin and nature of such dysfunction is still under investigation, which is an issue...

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Detalles Bibliográficos
Autores principales: Victorino, Daniella B., Pinheiro, Daniel J. L. L., Scott-McKean, Jonah J., Barker, Sarah, Stasko, Melissa R., Faber, Jean, Scorza, Carla A., Costa, Alberto C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096846/
https://www.ncbi.nlm.nih.gov/pubmed/33947925
http://dx.doi.org/10.1038/s41598-021-89011-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096846/
https://www.ncbi.nlm.nih.gov/pubmed/33947925
http://dx.doi.org/10.1038/s41598-021-89011-y

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