High-throughput screening of natural compounds and inhibition of a major therapeutic target HsGSK-3β for Alzheimer’s disease using computational approaches

BACKGROUND: Alzheimer’s disease is a leading neurodegenerative disease worldwide and is the 6th leading cause of death in the USA. AD is a very complex disease and the drugs available in the market cannot fully cure it. The glycogen synthase kinase 3 beta plays a major role in the hyperphosphorylati...

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Detalles Bibliográficos
Autores principales: Shukla, Rohit, Singh, Tiratha Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096881/
https://www.ncbi.nlm.nih.gov/pubmed/33945025
http://dx.doi.org/10.1186/s43141-021-00163-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096881/
https://www.ncbi.nlm.nih.gov/pubmed/33945025
http://dx.doi.org/10.1186/s43141-021-00163-w

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