Altered Phase Separation and Cellular Impact in C9orf72-Linked ALS/FTD

Since the discovery of the C9orf72 repeat expansion mutation as causative for chromosome 9-linked amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in 2011, a multitude of cellular pathways have been implicated. However, evidence has also been accumulating for a key mechanism of...

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Detalles Bibliográficos
Autores principales: Solomon, Daniel A., Smikle, Rebekah, Reid, Matthew J., Mizielinska, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096919/
https://www.ncbi.nlm.nih.gov/pubmed/33967699
http://dx.doi.org/10.3389/fncel.2021.664151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096919/
https://www.ncbi.nlm.nih.gov/pubmed/33967699
http://dx.doi.org/10.3389/fncel.2021.664151

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