Moderate DNA hypomethylation suppresses intestinal tumorigenesis by promoting caspase-3 expression and apoptosis

Global DNA hypomethylation is a most common epigenetic alteration in human neoplasia. However, accumulative evidence shows that global DNA hypomethylation impacts tumorigenesis in a tissue-specific manner, promoting tumorigenesis in some but suppressing tumorigenesis in others including colorectal c...

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Detalles Bibliográficos
Autores principales: Duan, Xiaoya, Huang, Yuanyong, Chen, Xiaoxing, Wang, Wencai, Chen, Jiwei, Li, Jialun, Yang, Wei, Li, Jiwen, Wu, Qihan, Wong, Jiemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096944/
https://www.ncbi.nlm.nih.gov/pubmed/33947834
http://dx.doi.org/10.1038/s41389-021-00328-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096944/
https://www.ncbi.nlm.nih.gov/pubmed/33947834
http://dx.doi.org/10.1038/s41389-021-00328-9

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