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Kinetic resolution of indolines by asymmetric hydroxylamine formation

Catalytic kinetic resolution of amines represents a longstanding challenge in chemical synthesis. Here, we described a kinetic resolution of secondary amines through oxygenation to produce enantiopure hydroxylamines involving N–O bond formation. The economic and practical titanium-catalyzed asymmetr...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Lu, Ran, He, Chuangchuang, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096955/
https://www.ncbi.nlm.nih.gov/pubmed/33947847
http://dx.doi.org/10.1038/s41467-021-22658-3