Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo

Differential transcription of identical DNA sequences leads to distinct tissue lineages and then multiple cell types within a lineage, an epigenetic process central to progenitor and stem cell biology. The associated genome-wide changes, especially in native tissues, remain insufficiently understood...

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Detalles Bibliográficos
Autores principales: Little, Danielle R., Lynch, Anne M., Yan, Yun, Akiyama, Haruhiko, Kimura, Shioko, Chen, Jichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096971/
https://www.ncbi.nlm.nih.gov/pubmed/33947861
http://dx.doi.org/10.1038/s41467-021-22817-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096971/
https://www.ncbi.nlm.nih.gov/pubmed/33947861
http://dx.doi.org/10.1038/s41467-021-22817-6

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