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Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo
Differential transcription of identical DNA sequences leads to distinct tissue lineages and then multiple cell types within a lineage, an epigenetic process central to progenitor and stem cell biology. The associated genome-wide changes, especially in native tissues, remain insufficiently understood...
Autores principales: | Little, Danielle R., Lynch, Anne M., Yan, Yun, Akiyama, Haruhiko, Kimura, Shioko, Chen, Jichao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096971/ https://www.ncbi.nlm.nih.gov/pubmed/33947861 http://dx.doi.org/10.1038/s41467-021-22817-6 |
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