GIPC2 is an endocrine-specific tumor suppressor gene for both sporadic and hereditary tumors of RET- and SDHB-, but not VHL-associated clusters of pheochromocytoma/paraganglioma

Pheochromocytoma/paraganglioma (PPGL) is an endocrine tumor of the chromaffin cells in the adrenal medulla or the paraganglia. Currently, about 70% of PPGLs can be explained by germline or somatic mutations in several broadly expressed susceptibility genes including RET, VHL, and SDHB, while for the...

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Detalles Bibliográficos
Autores principales: Dong, Yeqing, Huang, Yongsheng, Fan, Chengyan, Wang, Liang, Zhang, Ran, Li, Wenhua, Guo, Zhengguang, Wang, Dong, Zheng, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096975/
https://www.ncbi.nlm.nih.gov/pubmed/33947839
http://dx.doi.org/10.1038/s41419-021-03731-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096975/
https://www.ncbi.nlm.nih.gov/pubmed/33947839
http://dx.doi.org/10.1038/s41419-021-03731-7

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