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Detectable Unmetabolized Folic Acid and Elevated Folate Concentrations in Folic Acid-Supplemented Canadian Children With Sickle Cell Disease

Sickle cell disease (SCD) is an inherited hemoglobinopathy caused by a variant (rs344) in the HBB gene encoding the β-globin subunit of hemoglobin. Chronic hemolytic anemia and increased erythropoiesis and RBC turnover in individuals with SCD can result in increased needs for folate and other B-vita...

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Detalles Bibliográficos
Autores principales: Williams, Brock A., Mayer, Cara, McCartney, Heather, Devlin, Angela M., Lamers, Yvonne, Vercauteren, Suzanne M., Wu, John K., Karakochuk, Crystal D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096995/
https://www.ncbi.nlm.nih.gov/pubmed/33968971
http://dx.doi.org/10.3389/fnut.2021.642306