Gene-environment dependencies lead to collider bias in models with polygenic scores

The application of polygenic scores has transformed our ability to investigate whether and how genetic and environmental factors jointly contribute to the variation of complex traits. Modelling the complex interplay between genes and environment, however, raises serious methodological challenges. He...

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Detalles Bibliográficos
Autores principales: Akimova, Evelina T., Breen, Richard, Brazel, David M., Mills, Melinda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097011/
https://www.ncbi.nlm.nih.gov/pubmed/33947934
http://dx.doi.org/10.1038/s41598-021-89020-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097011/
https://www.ncbi.nlm.nih.gov/pubmed/33947934
http://dx.doi.org/10.1038/s41598-021-89020-x

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