Cargando…

MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells

Haematopoietic stem cells (HSCs) tightly regulate their quiescence, proliferation, and differentiation to generate blood cells during the entire lifetime. The mechanisms by which these critical activities are balanced are still unclear. Here, we report that Macrophage-Erythroblast Attacher (MAEA, al...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Qiaozhi, Pinho, Sandra, Dong, Shuxian, Pierce, Halley, Li, Huihui, Nakahara, Fumio, Xu, Jianing, Xu, Chunliang, Boulais, Philip E., Zhang, Dachuan, Maryanovich, Maria, Cuervo, Ana Maria, Frenette, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097058/
https://www.ncbi.nlm.nih.gov/pubmed/33947846
http://dx.doi.org/10.1038/s41467-021-22749-1