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Heterologous protection against malaria by a simple chemoattenuated PfSPZ vaccine regimen in a randomized trial
Immunization with Plasmodium falciparum (Pf) sporozoites under chemoprophylaxis (PfSPZ-CVac) is the most efficacious approach to malaria vaccination. Implementation is hampered by a complex chemoprophylaxis regimen and missing evidence for efficacy against heterologous infection. We report the resul...
Autores principales: | Sulyok, Zita, Fendel, Rolf, Eder, Bianca, Lorenz, Freia-Raphaella, KC, Natasha, Karnahl, Matthias, Lalremruata, Albert, Nguyen, The T., Held, Jana, Adjadi, Folashade Almeine Cyntiche, Klockenbring, Torsten, Flügge, Judith, Woldearegai, Tamirat Gebru, Lamsfus Calle, Carlos, Ibáñez, Javier, Rodi, Miriam, Egger-Adam, Diane, Kreidenweiss, Andrea, Köhler, Carsten, Esen, Meral, Sulyok, Mihály, Manoj, Anita, Richie, Thomas L., Sim, B. Kim Lee, Hoffman, Stephen L., Mordmüller, Benjamin, Kremsner, Peter G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097064/ https://www.ncbi.nlm.nih.gov/pubmed/33947856 http://dx.doi.org/10.1038/s41467-021-22740-w |
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