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Targeted Thrombospondin-1 Expression in Ocular Vascular Development and Neovascularization

Tight regulation of positive and negative regulators of angiogenesis is essential, particularly in the eye where their dysregulation can lead to vision loss. Thrombospondin-1 (TSP1) is a matricellular protein that negatively regulates angiogenesis and inflammation in the eye. It aids ocular vascular...

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Detalles Bibliográficos
Autores principales: Sorenson, Christine M., Wang, Shoujian, Darjatmoko, Soesiawati R., Gurel, Zafer, Liu, Bo, Sheibani, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097095/
https://www.ncbi.nlm.nih.gov/pubmed/33968943
http://dx.doi.org/10.3389/fcell.2021.671989