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Targeted Thrombospondin-1 Expression in Ocular Vascular Development and Neovascularization
Tight regulation of positive and negative regulators of angiogenesis is essential, particularly in the eye where their dysregulation can lead to vision loss. Thrombospondin-1 (TSP1) is a matricellular protein that negatively regulates angiogenesis and inflammation in the eye. It aids ocular vascular...
Autores principales: | Sorenson, Christine M., Wang, Shoujian, Darjatmoko, Soesiawati R., Gurel, Zafer, Liu, Bo, Sheibani, Nader |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097095/ https://www.ncbi.nlm.nih.gov/pubmed/33968943 http://dx.doi.org/10.3389/fcell.2021.671989 |
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