Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos

Aconitine (AC), one of the bioactive diterpenoid alkaloids extracted from Aconitum plants, is widely used in traditional herbal medicine to treat various diseases. Emerging evidence indicates that AC has attracted great interest for its wide cardiotoxicity and neurotoxicity. However, the toxic effec...

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Detalles Bibliográficos
Autores principales: Xia, Qing, Gao, Shuo, Rapael Gnanamuthu, Samuel Rajendran, Zhuang, Kaiyan, Song, Zhenzhen, Zhang, Yun, Wang, Xue, Tu, Pengfei, Li, Jianheng, Liu, Kechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097150/
https://www.ncbi.nlm.nih.gov/pubmed/33967776
http://dx.doi.org/10.3389/fphar.2021.642480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097150/
https://www.ncbi.nlm.nih.gov/pubmed/33967776
http://dx.doi.org/10.3389/fphar.2021.642480

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