A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells

The molecular mechanisms and forces involved in the translocation of bacterial toxins into host cells are still a matter of intense research. The adenylate cyclase (CyaA) toxin from Bordetella pertussis displays a unique intoxication pathway in which its catalytic domain is directly translocated acr...

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Detalles Bibliográficos
Autores principales: Voegele, Alexis, Sadi, Mirko, O'Brien, Darragh Patrick, Gehan, Pauline, Raoux‐Barbot, Dorothée, Davi, Maryline, Hoos, Sylviane, Brûlé, Sébastien, Raynal, Bertrand, Weber, Patrick, Mechaly, Ariel, Haouz, Ahmed, Rodriguez, Nicolas, Vachette, Patrice, Durand, Dominique, Brier, Sébastien, Ladant, Daniel, Chenal, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097335/
https://www.ncbi.nlm.nih.gov/pubmed/33977052
http://dx.doi.org/10.1002/advs.202003630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097335/
https://www.ncbi.nlm.nih.gov/pubmed/33977052
http://dx.doi.org/10.1002/advs.202003630

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