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Genome diversity and instability in human germ cells and preimplantation embryos

Genome diversity is essential for evolution and is of fundamental importance to human health. Generating genome diversity requires phases of DNA damage and repair that can cause genome instability. Humans have a high incidence of de novo congenital disorders compared to other organisms. Recent acces...

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Detalles Bibliográficos
Autores principales: Shukla, Vallari, Høffding, Miya Kudo, Hoffmann, Eva R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097364/
https://www.ncbi.nlm.nih.gov/pubmed/33500205
http://dx.doi.org/10.1016/j.semcdb.2020.12.007