The Antibiotic Negamycin Crosses the Bacterial Cytoplasmic Membrane by Multiple Routes

Negamycin is a natural pseudodipeptide antibiotic with promising activity against Gram-negative and Gram-positive bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, and Staphylococcus aureus, and good efficacy in infection models. It binds to ribosomes with a novel binding mode, stimula...

Descripción completa

Detalles Bibliográficos
Autores principales: Hörömpöli, Daniel, Ciglia, Catherine, Glüsenkamp, Karl-Heinz, Haustedt, Lars Ole, Falkenstein-Paul, Hildegard, Bendas, Gerd, Berscheid, Anne, Brötz-Oesterhelt, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097410/
https://www.ncbi.nlm.nih.gov/pubmed/33468467
http://dx.doi.org/10.1128/AAC.00986-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097410/
https://www.ncbi.nlm.nih.gov/pubmed/33468467
http://dx.doi.org/10.1128/AAC.00986-20

Ejemplares similares