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The Antibiotic Negamycin Crosses the Bacterial Cytoplasmic Membrane by Multiple Routes

Negamycin is a natural pseudodipeptide antibiotic with promising activity against Gram-negative and Gram-positive bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, and Staphylococcus aureus, and good efficacy in infection models. It binds to ribosomes with a novel binding mode, stimula...

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Detalles Bibliográficos
Autores principales:	Hörömpöli, Daniel, Ciglia, Catherine, Glüsenkamp, Karl-Heinz, Haustedt, Lars Ole, Falkenstein-Paul, Hildegard, Bendas, Gerd, Berscheid, Anne, Brötz-Oesterhelt, Heike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097410/ https://www.ncbi.nlm.nih.gov/pubmed/33468467 http://dx.doi.org/10.1128/AAC.00986-20

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