In Vitro and In Vivo Antibacterial Activities of a Novel Quinolone Compound, OPS-2071, against Clostridioides difficile

OPS-2071 is a novel quinolone antibacterial agent characterized by low oral absorption that reduces the risk of adverse events typical of fluoroquinolone class antibiotics. The in vitro and in vivo antibacterial activities of OPS-2071 against Clostridioides difficile were evaluated in comparison to...

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Detalles Bibliográficos
Autores principales: Oka, Daisuke, Yamaya, Naomitsu, Kuno, Takuya, Asakawa, Yuta, Shiragiku, Toshiyuki, Chen, Liang, Xue, Jingbo, Mamuti, Abudusaimi, Ye, Fangguo, Sun, Jiangqin, Ohguro, Kinue, Miyamoto, Hisashi, Uematsu, Yukitaka, Inagaki, Katsuya, Cheng, Jie-Fei, Matsumoto, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097418/
https://www.ncbi.nlm.nih.gov/pubmed/33495229
http://dx.doi.org/10.1128/AAC.01170-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097418/
https://www.ncbi.nlm.nih.gov/pubmed/33495229
http://dx.doi.org/10.1128/AAC.01170-20

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