Parasite-Host Dynamics throughout Antimalarial Drug Development Stages Complicate the Translation of Parasite Clearance

Ensuring continued success against malaria depends on a pipeline of new antimalarials. Antimalarial drug development utilizes preclinical murine and experimental human malaria infection studies to evaluate drug efficacy. A sequential approach is typically adapted, with results from each stage inform...

Descripción completa

Detalles Bibliográficos
Autores principales: Burgert, Lydia, Zaloumis, Sophie, Dini, Saber, Marquart, Louise, Cao, Pengxing, Cherkaoui, Mohammed, Gobeau, Nathalie, McCarthy, James, Simpson, Julie A., Möhrle, Jörg J., Penny, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097426/
https://www.ncbi.nlm.nih.gov/pubmed/33526486
http://dx.doi.org/10.1128/AAC.01539-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097426/
https://www.ncbi.nlm.nih.gov/pubmed/33526486
http://dx.doi.org/10.1128/AAC.01539-20

Ejemplares similares