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Parasite-Host Dynamics throughout Antimalarial Drug Development Stages Complicate the Translation of Parasite Clearance
Ensuring continued success against malaria depends on a pipeline of new antimalarials. Antimalarial drug development utilizes preclinical murine and experimental human malaria infection studies to evaluate drug efficacy. A sequential approach is typically adapted, with results from each stage inform...
Autores principales: | Burgert, Lydia, Zaloumis, Sophie, Dini, Saber, Marquart, Louise, Cao, Pengxing, Cherkaoui, Mohammed, Gobeau, Nathalie, McCarthy, James, Simpson, Julie A., Möhrle, Jörg J., Penny, Melissa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097426/ https://www.ncbi.nlm.nih.gov/pubmed/33526486 http://dx.doi.org/10.1128/AAC.01539-20 |
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