Efficient Treatment of Experimental Cerebral Malaria by an Artemisone-SMEDDS System: Impact of Application Route and Dosing Frequency

Artemisone (ART) has been successfully tested in vitro and in animal models against several diseases. However, its poor aqueous solubility and limited chemical stability are serious challenges. We developed a self-microemulsifying drug delivery system (SMEDDS) that overcomes these limitations. Here,...

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Detalles Bibliográficos
Autores principales: Zech, Johanna, Salaymeh, Nadeen, Hunt, Nicholas H., Mäder, Karsten, Golenser, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097435/
https://www.ncbi.nlm.nih.gov/pubmed/33558284
http://dx.doi.org/10.1128/AAC.02106-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097435/
https://www.ncbi.nlm.nih.gov/pubmed/33558284
http://dx.doi.org/10.1128/AAC.02106-20

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