Drug-Drug Interaction Study of Benznidazole and E1224 in Healthy Male Volunteers

E1224 is a prodrug of ravuconazole (RVZ), an antifungal drug with promising anti-Trypanosoma cruzi activity, the causative organism of Chagas disease (CD). This study was designed to assess the pharmacokinetics (PK) and safety interactions of benznidazole (BNZ), the drug of choice for treatment of C...

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Detalles Bibliográficos
Autores principales: Ribeiro, Isabela, Blum, Bethania, Fernandes, Jayme, Santina, Glaucia, Asada, Makoto, Everson, Michael, Schuck, Edgar, Feleder, Ethel, Evene, Eric, Gualano, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097458/
https://www.ncbi.nlm.nih.gov/pubmed/33558286
http://dx.doi.org/10.1128/AAC.02150-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097458/
https://www.ncbi.nlm.nih.gov/pubmed/33558286
http://dx.doi.org/10.1128/AAC.02150-19

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