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Association of TYK2 polymorphisms with autoimmune diseases: A comprehensive and updated systematic review with meta-analysis
Autoimmune diseases are characterized by the loss of self-tolerance, leading to immune-mediated tissue destruction and chronic inflammation. Tyrosine kinase 2 (TYK2) protein plays a key role in immunity and apoptosis pathways. Studies have reported associations between single nucleotide polymorphism...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097517/ https://www.ncbi.nlm.nih.gov/pubmed/33949620 http://dx.doi.org/10.1590/1678-4685-GMB-2020-0425 |