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Association of TYK2 polymorphisms with autoimmune diseases: A comprehensive and updated systematic review with meta-analysis

Autoimmune diseases are characterized by the loss of self-tolerance, leading to immune-mediated tissue destruction and chronic inflammation. Tyrosine kinase 2 (TYK2) protein plays a key role in immunity and apoptosis pathways. Studies have reported associations between single nucleotide polymorphism...

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Detalles Bibliográficos
Autores principales: Pellenz, Felipe Mateus, Dieter, Cristine, Lemos, Natália Emerim, Bauer, Andrea Carla, de Souza, Bianca Marmontel, Crispim, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097517/
https://www.ncbi.nlm.nih.gov/pubmed/33949620
http://dx.doi.org/10.1590/1678-4685-GMB-2020-0425