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PBSIM2: a simulator for long-read sequencers with a novel generative model of quality scores
MOTIVATION: Recent advances in high-throughput long-read sequencers, such as PacBio and Oxford Nanopore sequencers, produce longer reads with more errors than short-read sequencers. In addition to the high error rates of reads, non-uniformity of errors leads to difficulties in various downstream ana...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097687/ https://www.ncbi.nlm.nih.gov/pubmed/32976553 http://dx.doi.org/10.1093/bioinformatics/btaa835 |