Progress towards an inducible, replication-proficient transposon delivery vector for Chlamydia trachomatis

Background Genetic systems have been developed for Chlamydia but the extremely low transformation frequency remains a significant bottleneck.  Our goal is to develop a self-replicating transposon delivery vector for C. trachomatis which can be expanded prior to transposase induction. Methods We made...

Descripción completa

Detalles Bibliográficos
Autores principales: Skilton, Rachel J., O'Neill, Colette, Thomson, Nicholas R., Lampe, David J., Clarke, Ian N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097735/
https://www.ncbi.nlm.nih.gov/pubmed/33997299
http://dx.doi.org/10.12688/wellcomeopenres.16665.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097735/
https://www.ncbi.nlm.nih.gov/pubmed/33997299
http://dx.doi.org/10.12688/wellcomeopenres.16665.1

Ejemplares similares