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Progress towards an inducible, replication-proficient transposon delivery vector for Chlamydia trachomatis
Background Genetic systems have been developed for Chlamydia but the extremely low transformation frequency remains a significant bottleneck. Our goal is to develop a self-replicating transposon delivery vector for C. trachomatis which can be expanded prior to transposase induction. Methods We made...
Autores principales: | Skilton, Rachel J., O'Neill, Colette, Thomson, Nicholas R., Lampe, David J., Clarke, Ian N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097735/ https://www.ncbi.nlm.nih.gov/pubmed/33997299 http://dx.doi.org/10.12688/wellcomeopenres.16665.1 |
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