H3K14 hyperacetylation-mediated c-Myc binding to the miR-30a-5p gene promoter under hypoxia postconditioning protects senescent cardiomyocytes from hypoxia/reoxygenation injury

Our previous study reported that microRNA (miR)-30a-5p upregulation under hypoxia postconditioning (HPostC) exert a protective effect on aged H9C2 cells against hypoxia/reoxygenation injury via DNA methyltransferase 3B-induced DNA hypomethylation at the miR-30a-5p gene promoter. This suggests that m...

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Detalles Bibliográficos
Autores principales: Xu, Lingbo, Zhang, Huiping, Wang, Yanhua, Guo, Wei, Gu, Lingyu, Yang, Anning, Ma, Shengchao, Yang, Yong, Wu, Kai, Jiang, Yideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097758/
https://www.ncbi.nlm.nih.gov/pubmed/33880587
http://dx.doi.org/10.3892/mmr.2021.12107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097758/
https://www.ncbi.nlm.nih.gov/pubmed/33880587
http://dx.doi.org/10.3892/mmr.2021.12107

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