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Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain
BACKGROUND: Parkinson’s disease (PD) is a complex, age-related neurodegenerative disorder of largely unknown etiology. PD is strongly associated with mitochondrial respiratory dysfunction, which can lead to epigenetic dysregulation and specifically altered histone acetylation. Nevertheless, and desp...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097820/ https://www.ncbi.nlm.nih.gov/pubmed/33947435 http://dx.doi.org/10.1186/s13024-021-00450-7 |