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Sustained delivery of MMP-9 siRNA via thermosensitive hydrogel accelerates diabetic wound healing

Excessive expression of matrix metalloproteinase 9 (MMP-9) impedes healing of diabetic chronic wounds, thus wound dressing that could effectively inhibit the expression of MMP-9 offers significant clinical translation for diabetic wound healing. Herein, a hybrid hydrogel dressing was developed for l...

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Detalles Bibliográficos
Autores principales: Lan, Biyun, Zhang, Liming, Yang, Liqun, Wu, Junfeng, Li, Na, Pan, Chenglin, Wang, Xiaoyi, Zeng, Lexiang, Yan, Li, Yang, Chuan, Ren, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097905/
https://www.ncbi.nlm.nih.gov/pubmed/33952251
http://dx.doi.org/10.1186/s12951-021-00869-6