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Short‐term rapamycin administration elevated testosterone levels and exacerbated reproductive disorder in dehydroepiandrosterone‐induced polycystic ovary syndrome mice

BACKGROUND: Polycystic ovary syndrome (PCOS) is a multifactorial endocrinopathy that affects reproduction and metabolism. Mammalian target of rapamycin (mTOR) has been shown to participate in female reproduction under physiological and pathological conditions. This study aimed to investigate the rol...

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Detalles Bibliográficos
Autores principales: Guo, Zaixin, Chen, Xiaohan, Feng, Penghui, Yu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097915/
https://www.ncbi.nlm.nih.gov/pubmed/33947426
http://dx.doi.org/10.1186/s13048-021-00813-0