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Synthesis, biological evaluation and docking studies of 1,2,4-oxadiazole linked 5-fluorouracil derivatives as anticancer agents

BACKGROUND: 1,2,4-oxadiazole derivatives exhibited significant anti-cancer activity when they were evaluated, against human cancer cell lines. They also showed anti-inflammatory, analgesic, diabetic, immunosuppressive, α,β(3)-receptor antagonist, antimicrobial, anti-helminthic, histamine-H3 and anti...

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Detalles Bibliográficos
Autores principales: Bommera, Ravi Kumar, Kethireddy, Shashikala, Govindapur, Rajeshwar Reddy, Eppakayala, Laxminarayana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097950/
https://www.ncbi.nlm.nih.gov/pubmed/33947440
http://dx.doi.org/10.1186/s13065-021-00757-y