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Optimized cryo-EM data-acquisition workflow by sample-thickness determination
Sample thickness is a known key parameter in cryo-electron microscopy (cryo-EM) and can affect the amount of high-resolution information retained in the image. Yet, common data-acquisition approaches in single-particle cryo-EM do not take it into account. Here, it is demonstrated how the sample thic...
Autores principales: | Rheinberger, Jan, Oostergetel, Gert, Resch, Guenter P., Paulino, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098475/ https://www.ncbi.nlm.nih.gov/pubmed/33950013 http://dx.doi.org/10.1107/S205979832100334X |
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