Peptide-based inhibitors of protein–protein interactions: biophysical, structural and cellular consequences of introducing a constraint

Protein–protein interactions (PPIs) are implicated in the majority of cellular processes by enabling and regulating the function of individual proteins. Thus, PPIs represent high-value, but challenging targets for therapeutic intervention. The development of constrained peptides represents an emergi...

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Detalles Bibliográficos
Autores principales: Wang, Hongshuang, Dawber, Robert S., Zhang, Peiyu, Walko, Martin, Wilson, Andrew J., Wang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098664/
https://www.ncbi.nlm.nih.gov/pubmed/33995995
http://dx.doi.org/10.1039/d1sc00165e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098664/
https://www.ncbi.nlm.nih.gov/pubmed/33995995
http://dx.doi.org/10.1039/d1sc00165e

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