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Constitutive Musashi1 expression impairs mouse postnatal development and intestinal homeostasis

Evolutionarily conserved RNA-binding protein Musashi1 (Msi1) can regulate developmentally relevant genes. Here we report the generation and characterization of a mouse model that allows inducible Msi1 overexpression in a temporal and tissue-specific manner. We show that ubiquitous Msi1 induction in...

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Detalles Bibliográficos
Autores principales: Chiremba, Thelma T., Neufeld, Kristi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098822/
https://www.ncbi.nlm.nih.gov/pubmed/33175598
http://dx.doi.org/10.1091/mbc.E20-03-0206