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Constitutive Musashi1 expression impairs mouse postnatal development and intestinal homeostasis
Evolutionarily conserved RNA-binding protein Musashi1 (Msi1) can regulate developmentally relevant genes. Here we report the generation and characterization of a mouse model that allows inducible Msi1 overexpression in a temporal and tissue-specific manner. We show that ubiquitous Msi1 induction in...
Autores principales: | Chiremba, Thelma T., Neufeld, Kristi L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098822/ https://www.ncbi.nlm.nih.gov/pubmed/33175598 http://dx.doi.org/10.1091/mbc.E20-03-0206 |
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