Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10

Insulin controls glucose uptake into muscle and fat cells by inducing a net redistribution of glucose transporter 4 (GLUT4) from intracellular storage to the plasma membrane (PM). The TBC1D4-RAB10 signaling module is required for insulin-stimulated GLUT4 translocation to the PM, although where it in...

Descripción completa

Detalles Bibliográficos
Autores principales: Brumfield, Alexandria, Chaudhary, Natasha, Molle, Dorothee, Wen, Jennifer, Graumann, Johannes, McGraw, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098823/
https://www.ncbi.nlm.nih.gov/pubmed/33175605
http://dx.doi.org/10.1091/mbc.E20-06-0356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098823/
https://www.ncbi.nlm.nih.gov/pubmed/33175605
http://dx.doi.org/10.1091/mbc.E20-06-0356

Ejemplares similares