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Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10

Insulin controls glucose uptake into muscle and fat cells by inducing a net redistribution of glucose transporter 4 (GLUT4) from intracellular storage to the plasma membrane (PM). The TBC1D4-RAB10 signaling module is required for insulin-stimulated GLUT4 translocation to the PM, although where it in...

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Detalles Bibliográficos
Autores principales:	Brumfield, Alexandria, Chaudhary, Natasha, Molle, Dorothee, Wen, Jennifer, Graumann, Johannes, McGraw, Timothy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098823/ https://www.ncbi.nlm.nih.gov/pubmed/33175605 http://dx.doi.org/10.1091/mbc.E20-06-0356

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