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Uveal melanoma cells use ameboid and mesenchymal mechanisms of cell motility crossing the endothelium

Uveal melanomas (UMs) are malignant cancers arising from the pigmented layers of the eye. UM cells spread through the bloodstream, and circulating UM cells are detectable in patients before metastases appear. Extravasation of UM cells is necessary for formation of metastases, and transendothelial mi...

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Detalles Bibliográficos
Autores principales: Onken, Michael D., Blumer, Kendall J., Cooper, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098856/
https://www.ncbi.nlm.nih.gov/pubmed/33405963
http://dx.doi.org/10.1091/mbc.E20-04-0241