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Airway macrophage-intrinsic TGF-β1 regulates pulmonary immunity during early-life allergen exposure
BACKGROUND: Early life represents a major risk window for asthma development. However, the mechanisms controlling the threshold for establishment of allergic airway inflammation in early life are incompletely understood. Airway macrophages (AMs) regulate pulmonary allergic responses and undergo TGF-...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mosby
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098862/ https://www.ncbi.nlm.nih.gov/pubmed/33571538 http://dx.doi.org/10.1016/j.jaci.2021.01.026 |