Airway macrophage-intrinsic TGF-β1 regulates pulmonary immunity during early-life allergen exposure

BACKGROUND: Early life represents a major risk window for asthma development. However, the mechanisms controlling the threshold for establishment of allergic airway inflammation in early life are incompletely understood. Airway macrophages (AMs) regulate pulmonary allergic responses and undergo TGF-...

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Detalles Bibliográficos
Autores principales: Branchett, William J., Cook, James, Oliver, Robert A., Bruno, Nicoletta, Walker, Simone A., Stölting, Helen, Mack, Matthias, O’Garra, Anne, Saglani, Sejal, Lloyd, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2021
Materias:
Mechanisms of Allergy/Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098862/
https://www.ncbi.nlm.nih.gov/pubmed/33571538
http://dx.doi.org/10.1016/j.jaci.2021.01.026

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