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Drp1‐dependent peptide reverse mitochondrial fragmentation, a homeostatic response in Friedreich ataxia

Friedreich ataxia is an autosomal recessive, neurodegenerative disease characterized by the deficiency of the iron‐sulfur cluster assembly protein frataxin. Loss of this protein impairs mitochondrial function. Mitochondria alter their morphology in response to various stresses; however, such alterat...

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Detalles Bibliográficos
Autores principales: Johnson, Joseph, Mercado‐Ayón, Elizabeth, Clark, Elisia, Lynch, David, Lin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099044/
https://www.ncbi.nlm.nih.gov/pubmed/33951329
http://dx.doi.org/10.1002/prp2.755