Cargando…
Drp1‐dependent peptide reverse mitochondrial fragmentation, a homeostatic response in Friedreich ataxia
Friedreich ataxia is an autosomal recessive, neurodegenerative disease characterized by the deficiency of the iron‐sulfur cluster assembly protein frataxin. Loss of this protein impairs mitochondrial function. Mitochondria alter their morphology in response to various stresses; however, such alterat...
Autores principales: | Johnson, Joseph, Mercado‐Ayón, Elizabeth, Clark, Elisia, Lynch, David, Lin, Hong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099044/ https://www.ncbi.nlm.nih.gov/pubmed/33951329 http://dx.doi.org/10.1002/prp2.755 |
Ejemplares similares
-
Role of frataxin protein deficiency and metabolic dysfunction in Friedreich ataxia, an autosomal recessive mitochondrial disease
por: Clark, Elisia, et al.
Publicado: (2018) -
Selected missense mutations impair frataxin processing in Friedreich ataxia
por: Clark, Elisia, et al.
Publicado: (2017) -
Identification of a novel missense mutation in Friedreich's ataxia –FXN(W)
(168R)
por: Clark, Elisia, et al.
Publicado: (2019) -
Cerebellar Pathology in an Inducible Mouse Model of Friedreich Ataxia
por: Mercado-Ayón, Elizabeth, et al.
Publicado: (2022) -
Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia
por: Lin, Hong, et al.
Publicado: (2017)