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Machine-learning a virus assembly fitness landscape
Realistic evolutionary fitness landscapes are notoriously difficult to construct. A recent cutting-edge model of virus assembly consists of a dodecahedral capsid with 12 corresponding packaging signals in three affinity bands. This whole genome/phenotype space consisting of 3(12) genomes has been ex...
Autores principales: | Dechant, Pierre-Philippe, He, Yang-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099058/ https://www.ncbi.nlm.nih.gov/pubmed/33951035 http://dx.doi.org/10.1371/journal.pone.0250227 |
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