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Intracerebroventricular delivery of vascular endothelial growth factor in patients with amyotrophic lateral sclerosis, a phase I study

We studied the feasibility, safety, tolerability and pharmacokinetics of intracerebroventricular delivery of recombinant human vascular endothelial growth factor in patients with amyotrophic lateral sclerosis. In this phase I study in patients with amyotrophic lateral sclerosis, the study drug was d...

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Detalles Bibliográficos
Autores principales: Van Damme, Philip, Tilkin, Petra, Mercer, Katarina Jansson, Terryn, Joke, D’Hondt, Ann, Herne, Nina, Tousseyn, Thomas, Claeys, Kristl G, Thal, Dietmar R, Zachrisson, Olof, Almqvist, Per, Nuttin, Bart, Jerling, Markus, Bernadotte, Folke, Haegerstrand, Anders, Robberecht, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099230/
https://www.ncbi.nlm.nih.gov/pubmed/33977260
http://dx.doi.org/10.1093/braincomms/fcaa160