IL‐19 induced by IL‐13/IL‐17A in the nasal epithelium of patients with chronic rhinosinusitis upregulates MMP‐9 expression via ERK/NF‐κB signaling pathway

BACKGROUND: Tissue remodeling is a crucial characteristic of chronic rhinosinusitis (CRS). Imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) is crucial for the pathologic tissue remodeling in CRS. Elevation of interleukin (IL)‐19 or MMP‐9 levels i...

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Detalles Bibliográficos
Autores principales: Li, Xia, Huang, Jiancong, Chen, Xiaohong, Lai, Xiaoping, Huang, Zizhen, Li, Yue, Li, Shuaixiang, Chang, Lihong, Zhang, Gehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099262/
https://www.ncbi.nlm.nih.gov/pubmed/33900049
http://dx.doi.org/10.1002/clt2.12003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099262/
https://www.ncbi.nlm.nih.gov/pubmed/33900049
http://dx.doi.org/10.1002/clt2.12003

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